osawh  Strategic Biotech Merger/Acquisition OSA  www.osaglobalstrategicmanagement.com/index.html OSA  Global  and ADR Biotech Industry Corporate Performance, Pre and Post Mergers/ Acquisitions Performance Tracking

US and ADR Biotech Industry Corporate Performance,

US drug, biotech industry facing new drug supply shortage in pipeline, while existing patent
phasing out, and existing drug side effects led MERCK  and Pfizer stocks plunged 50 % and  resulted withdraw product  ( MS drug) from the markets led to ELAN stock plunged from 23 to 5 and  Biogen plunged from 70 to 40
Stocks                               outlook                           near term trading range
Merck ( MRK )   over reacted to side effect                38- 53
Pfizer  ( PFE)    recovering from side effect               25- 31
Biogen (BIIB)    recovering from side effect               35- 45
ELAN    (ELN)    recovering from product withdraw   5- 9
John-Johnson JNJ  steady growth in margin             50- 68
Genetech (DNA)  steady growth in margin                40- 55
Amgen  (AMGN)   steady growth in margin                 50- 66
Sanofi  (SNY)     steady growth in margin                  35- 45
Wyeth (WYE)     steady  growth in margin                 35- 44
Novartis (NVS)   steady growth in margin                  45- 55
MMSI                low margin                                       10- 15
STGN                low margin                                        7- 10
Martex (MATX) steady growth in margin                   40- 50 

Pre and Post Mergers/ Acquisitions Performance Tracking
Dec. 15, 2004

Johnson & Johnson 35 billion merger Guidant, 2 billion dollar sales , 400 million earning in heart stent, pace maker,
diversify into therapeutic area.  However Guidant is over priced  at 72,  Johnson may have some room to growth.
US Health Industry  mergers analysis, investment strategy: TYC merge MKD
High growth and high margin 12 %0Health equipment Tyco Intl (TYC) merge low growth and low margin 8 %
resperatory service Mallikrodt(MKD) will nt help near term TYC performance and stock prices, TYC stock stay 45-56, MKD in 30-35

OSA  May 29, 2000 Strategic alliance between Merck and Schering Plough in chloesterol drug developement and  Feb 3, 2000 analysis for Pfizer and WLM merger :  
Merck strategic alliance between Merck and Schering Plough in chloesterol drug developement
will not help near term profitability, However, it may help future R&D, MRK stock will be trded between 65 and 78, SGP   between 40 and58
AHP troubled by 2.5 bilion diet pills,stocks plunged from 75 to 40, weak in Biotech R&D will be benefited by WLM's strong R&D Lipitol cholestorol lowering drug , AHP stock will be traded bwtween 40and 45 as the deal failed, WLM profit margin still behind Amgen, Biogen.Stock prices after recent split rebound to 99 are over priced. The post merger integration cost saving benefits are over optimistic. Pfizer(PFE) acquired WLM , combined viagra and Lipitol will not help too much on their near term R&D drug pipeline, PFE and WLM PE ratio at 50 , it's hard to maintain over 20 % earning growth, PFE stock will still be between 25 and 43

(9806 analysis for Monsanto and American Home Products Merger) 
 Tracing results: Dr Huang accurately predicted in Sept 1998  that due to lack of new drug developements on both companies, the merger will not produce any near term fruitful result. The two companies drop the merger in mid Oct.
  Pre mergers OSA:  Drug and biotech industry is relative immune to the  Asian turmoil and strong dollar . Rather, it is more sensitive to the new drug commericalization and competition from the industry itself. Monsanto's  effort to move into biotech industry is not satisfying due to the lack of high end applications from the molecular, cellular, genetical lead to  relatively low profits margin ( 9 %)(only some success in the agricultural) like Amgen, Biogen. While AHP concentrated too much in conventional drugs which facing sharp competition. This merger does not improve it's competitive position in the Biotech in the immediate future     
 Post   mergers OSA:   Different cultural background and management concept requires Dr. Warren Huang over 30 years experiences in implementing quality, cost, market shares  goal, mission, performance oriented cross funtional pizza chart OSA strategic and execution OSA teams for US, Asian Paicifc multinationals provide unified manage ment  concept, procedures and decision methods supporting new corporate's restruct uring, reengineering efforts in new genetic engineered high profit drugs R & D and commercialization( Asian Pacific) strategy                                                               1      
Stock investment strategy after drop mergers:: but both  have to face the increasing competition in the biotech industry Monsanto  traded between 33 and 39,  AHP will be in the 42 to 51
991104 revision :However, Pharmacia merge Monsanto and Monsanto's recent  Celebrax success has offset it's loss in agriculutral loss, it's stock price will break 4 8to 65

Biotech Merger OSA experiences
Dr. Warren Huang have developement  Over ten  thousands  of  articificial intelligence, neural net, fuzzy logic, chaos algorithms based daily global interest rates, currency rates,  commodity, industrial raw matericals, IC and computers hadwares, financial futures, options prices, corporate profitability and stock prices  Operations Simulations Analysis  expert  systems, and implemented for US, Asian Pacific, European multinational oil, petro chemicals, information, biotech    industry corporate investment banking, restructuring, reengineering applications during the last 30 years (These systems have been recommend by US Hydrocarbon Processing Advanced Control and Information Management, Productivity and Quality, Process Design & Optimization Handbook during 1991- 1997,   Over 1000 major cos from 65  US, European, Asian Pacific, South American countries including EXXON, Dupont, BP, Shell, BASF, Aramco, Sinopec, IBM, Merck, Roche, Rhone-Poulenc etc. In addition to  thousands  corporate managers contacted 32 OSA based corporate  pre and post merger/acquistions  restructuring, reengineering performances analysis )and strategy, tracking, simulate daily  US Fed and global central bankers monetary policy, interest rates, currency, Asian financial crisis  and it's impact on global global commodity, industrial raw materials,  financial futures, options prices, corporate profitability, stock prices. Dr. Huang have directed over 300 senior graduate biochem, chemical eng. students to develope OSA approach to  molecular, celluar, gentic  based human biochem plant simulation, tracking, simulate, 30 causes  and cure of deseases, aging and conventional and biotech drug developement and performances, and implemented for drug and biotech industry pre and post merger/acqusition restructuring, reengineer ing and performances improvements simulation, investment, risk  managment for help ing  20 millions global  corporate CEO,  finance, import/ export,  currency, equities trading, procurement, marketing  managers, investors to take advantage of investment opportunities in last 20 years  financial crisis through the joint academic-industry, medical school, Hopsital,  biotech  training centers setup,  in OSA goal mission, performance oriented OSA teams directed by Dr. Warren Huang  to provide on the job training for biotech  industry corporate managers in  pre and post merger/acquisition   daily decision analysis      

US  weekly Fed and European, Asian central bankers  money supply,  fund rate, Asian Financial Crisis, Yen exchange  rate and new product developement impact on daily American Home Products and Monsanto   pre and post mergers performance OSA
Click here for  OSA based Biotech Developement and on the job training centers are available to the biotech industry and biotech security analysts   

Detailed analysis, stock investment research reports, simulation chart of the above and other Asian and European biotech corporate merger/acquisition  simulation results  are available by the order form below.      Key Benefits:     These BIotech industry  pre and post merger/acquistion OSA decision tools and OSA teams   management will provide billions dollars cost saving and with improved marketshare and profits and  help the global corporate CEO financial, procurement, marketing  on the job decisions analysis training  in global procurement, investment, marketing strategy,  to maximize  profit at minimum loss.

Also help investors  in global M/A investing.            

I email to   whaung3928@aol.com/  whuang@osawh.com

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