Dr. Huang has 32 years successful knowledge based online refinery, petrochemicals process plant OSA(Operations Simulation Analysis) and optimum computer control to provide optimum feedfoward setpoint control for improved plant operating quality, efficiency and plant life at reduced cost and accident, interruptions and reduced damage due to feedback control, without any laboratory or pilot plant tests, or equipment retrofit through OSA guided improved operating guideline and preventive maintenance.
He has extended this experience to human body biochemical plant design and operations simulation(OSA) andpharmaceutical products process simulations 14 years ago. directed over 300 senior chemical engineering and biochem senior and graduate students to conduct intensive search of global biotech literature, patents(including Chinese herbs)on cell development, genetic and molecular biology,immunology, cancer and virus caused major disease, and developed drugs process design simulation for 30 biotech drug process (from conventional penicillin, L-Lysine to Monoclonal antibody, interferon, to recombinant DNA)
Each person has his unique biochemical plant,
genetically inherited(design) and responding differently to the outside environmental
impact; pollution's, education's, working and emotional stress(operations). Even the
identical twin, will be difference if raised in different environment, as it is compared
to tow identical designed chemical plant behave differently if it is running under
different feed composition, or different climate. .All can be tracked by real time OSA.
Process plant central , auxiliary computer control and regulatory control systems is used
to simulation CNS(centrol Nervous control)Nervous systems control,PNS(Periphiral nervous
systems and Hormones self regulatory control to a presented setpoint for feedback
temperature control, water, chemical , energy balance, storage and self defense, emotional
response. while brain memory function compare to computer memory and programs.
The computer control systems consists of sensors and signals are sending through currents,
as compared to brain receive the senors signal from tongue, eyes, nose, and skins and send
the response through neurons send it through electrolyte neural transmitters in the spinal
cord (cable wire) and the receptors
while the local hormone regulars sending chemical signals through relay and enzyme
catalytic reactions amplified by second messengers and protein kinase to regulate the
control of reproduction and development. and interact with the CNS. and plays key role in
water, chemical balance and emotional, mood and organ functions. Again, by applying the
process plant optimum feedforward set point control can reduce body organ, tissue damage
due to offset in feedback control . In which modification of the setpoint due to inherited
habit (genetic defect or mutation, )is required to change the bad habit through preventive
medicine or health food to tune up the body system.
With Vera's assistance These biochemical plant is able to siumulate the actions at the
genetic and moelcular level real time human body biochemical plant Design and Operations
Simulation will help speedup the new drugs development by reduce or hopefully eventually
eliminate animal tests and clinical trials.
References:
Huang,W." Improve Process by OSA",-May 1980, Hydrocarbon Processing
Huang,W." OSA/DSA Approach to Biotech and Recombinant DNA",- int'l Biotech
Conference, Sept. 1985, Singapore
Huang,W" OSA/DSA Approach to Chemicals and Biotech Reactors", to ACHEMA, Sept.
1991, Frankfurt, Germany.
Huang,W, Huang, V." Human Body Biochemical Plant Design, Operations Simulation"-
Biotech Simulation Conf, July, 1998, Lyon,France
Huang,W, Huang, V"Aging, Disease, Therapy Operations Simulation",- Biotech
Simulation Conf, July, 1998, Lyon,France
To be presented to Int'l Biotech Simulation conference July 21-25, Lyon, France
Contact Information E-mail : whuang@osawh.com Fax : 1-510-524-4484( San Francisco, USA)
1999 osawh.com/黃華南博士版權所有 Copyright 1999 osawh.com/Dr.Warren Huang