He has developed, implemented the causes of diseases curing for over 30 drugs production process including antioxidants vitamin E, antibiotics, penicillin, and recombinant DNA approach to Insulin, Hepatitis, monoclonal antibodies, alpha, beta interferon. The results have been presented to global biotech Conferences and 1998 Nov. Int'l anti-cancer conference in Greece and Biotech simulation conference in Lyons,
in July.,Keystone Molecular Cell Biology conference, Colorado, USA, Feb 1999 on Cell,ular, moelcular, genentic approach to aging and cancer prevention and American Institute of Chemicals Engineers annual meeting, Dallas , Tx USA, Nov. 1999 Drug, Biotech division on Gall and mission oriented biotech research, training
This report consists of over 15 years
research conducted by Dr. Warren Huang, supervising 300 biochemical engineers in the
research of the molecular, celluar, genetic approach of the causes, cure, prevention of
human body diseases, cancer and aging and the last 5 years extensive review of books,
literatures, and joint research with Vera Huang at Molecular Cell Biology Department of
Univ of California, Berkeley, and attend numerous Nobel prize winners s on aging Prof.
Prusner on Alzheime. Prof. Baltimore on Immune, AIDS, and Prof. Goldstein on
Cholestrol control . and Dr. Huang'spersonal experiences with his friends associates over
100 years olds
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What
is Aging?
The biology of aging start human cell fail to repair, replicte the damaged cell due to
genetic mutation, environmental oxidative damaging on our DNA, fail to perform necessay
sigal transduction to maintan our peak efficiency
Why people aging : Our body time clock start aging, at the age of 25, our growth
horme production stops( all cell , organ, tissue are mature, stop growing) and most other
hormones production start decay at the rate of 5 % per year.
These hormones are necessary for cell growth and maintain peak immune defense
At what age people start aging ?
We often heard over the hill at 25. Bot men and women athlets have their peak perfomance
before 25, the golden era for physical performance and beauty, attractiveness. , However
the mental performcnce can continue to the 70's. aa we can we many scientist, literature,
musician still very sharp at 70's, , the barin weight (nerons) can increase with ages, as
you getting smarter as accumulation of intelligence.
What is the genetic and environmental impact on aging:
Only 40 % Aging is inherited from parents , while
environemental (diet, life style, and live philiosophy control 60 %
How long can we live and How to delay aging:
The oldest living person is from Russia peasant lived 140 years old. (cold country and
simple life)
while Japanese has average age of 82, because have light meal (steamed, boiled) and dring
green tea
French lives 78 also know as light diet, drink grape wine ( all good cancer, and high
blood pressure, heart attaction prevention diet)
aging, cancer prevention diets:
Natural Healing through Food remedy and improved life style
No smoking, no drinking ( only limited to one glass of wine per day. minimum 6-8
hours sleepr
Low fat, low calorie diet have been test on mouse to extend 40 % of live and observed on
human.
Daiy calorie standard : 1500 ,
avoid BBQ, charcoal broiled steaks, fired chichen mill, each mill account for 1000
calorie, and carcinogenic (cancer causing( must have plenty of vegetables, fruits with
such meal or take vitamin C supplement:
10 vegetables, fruit for cancer and aging prevention::
Broccoli, Cabbage, Califlower, Tomato, Corn, Carrots, Soybean/Tofu , Banna,
watermelon, grapefruit, grapes
Juices : grape, graefruit, cranberry, apple, orange, wine and green tea
basic meal, daily rice, bread, egg, milk, cerel, oatmeal, fish, some lean
meat, chicken
drink 4 glases of water:
This diet will kept daily calrie below 1500 and provide necessay vetable, animal protein,
vitamins for health maintainence of in moisture, tender skin, hair, tissue, organ, and
immune support for fight dieseases
This life style and life philosophy help you to live happy long life:
Happiness start from your positive
thinking inside you , not the wealth and friends surround you:
Goal, mission, performances oriented life, you are always at 18 with full ofd
dreams, and passionate of life and setting goal, mission, performance to
achieve your dream of truth, love , beauty come true.
Dr. Huang's thesis adviser, Dr. D. F. Othmer, a world renowned chemical engieeering prof ,
self made billionaire,
lived very simple fullfilled life, no entaintaing, (No TV radio in the house, dedicated to
his teaching and research work till he died at 102( reported on NY times We worked
till midnight for our paper for publication and encyclopedia. Last time I met him at his
90 birthday in Washington DC, We were invited to speak to American Institute of Chemicla
Engineers Diamond Jubilee meeting, he said, he enjoyed lecturing to 600 Beijin
University students
People at 18 have their dreams, as they getting older, they are frustrated, withdraw, or
retired, without any goal, dreams, they ages, suffered, heart attack, cancer..Anger,
depression are the no 1 enemy in cancer and aging(lead to p53 mutation, cell damage (Tumor
suppresor )
maintain physical and mentally active, watch your sitting position,, frequent
streching, do not sit and read, watch TV more than one hour without rest, stretching ( Dr
Huang does not wear eye glass)
You will be free from cancer, heart
failure, Alzheimer , back pain
Aging, diseases, cancer start with your
mind, your emotion and your life style, diet, finally your environemnt, genetically. This
diet and life styles have been used for most of authors's aged friends living
over 100, As most scientist, artists lived overy 90 on their dreams .
Anti-aging Hormone Therapy without Cancer:
Over 60 % of cancer are caused by smoking, high fat, high calorie diet and aging. While
most of the aging and cancer problems are caused by sharp hormone decline (woman after
menopause, men after 40 while the body stop producing growth hormone and DHEA, which play
important role in immune defense systems. Hormone replacement therapy to maintain body
normal function of the blood vessel and bones and heart operation and active happy sex
life even at some risk of cancer causes is justified. With the preventive measure in habit
and diets, cancer risks can be minimized (1 to 6 ) However, Molecular, Cellular, Genetic
Approach to Real Time(DSA/OSA ) Design and Operations Simulation of Aging, Hormone
Therapy, Cancer clinical test in animal and human body is vital for fighting Against aging
and cancer.
save 60 % of our cancer patients life with more than 60 % survival rate!
DSA/OSA applied to Real time Simulation and control , preventive maintenance of refinery,
petrochemicals, and biotech process performances
Dr. Warren Huang pioneered OSA (Design and Operations Simulations Analysis) by extended
the problem solving decision analysis of Operations Research used by US Aerospace
Automatic Guidance. Tracking, Simulation, applying artificial intelligence pattern
recognition, adaptive filtering and control to challenge the unknown and impossible task
for the Apollo moon landing to Chemical and biotech systems simulation.
As he implemented goal, mission, performance oriented multidisciplinary OSA planning,
execution teams to develop, implement decision support to Bethel and Mobil New York
office's and Stauffer Chemicals (subsidiary of Rhone Poulenc) process computer and
simulation methods section developed, implemented refinery, petrochemicals,
pharmaceuticals process design and operations simulation and control systems by
integrating the chemical, biochemical reactions engineering principle into senior process
engineers 20 years plant design, operating, equipment preventive maintenan ce's pattern
recognition, human mind reasoning knowledge and full range plant reactor catalyst, enzyme
loading, startup , daily reactor catalyst activity decay, operating, maintenance history
data, experiences as the information knowledge base. These knowledge based process
simulation systems were used directly for supporting senior engineers daily global
refinery, petrochemicals plant design, real time online tracking, simulation of reactors
and equipment design and operating environment and maintenance impact on the reaction
yields, performance improvement and on the job training, without going through laboratory
and pilot plant tests().( a well maintained and regular catalyst, enzyme replacement plant
can run 50 years life with minimum accidents compare to average 10
Real time Tracking of causes of Aging, human cancer and hormone
therapy, drug productions
Warren extended OSA to molecular, genetic, level human biochemical plant design and
operations simulation(7-9) for causes of aging, cancer and hormone therapy, drugs
production process simulations 14 years ago. He directed over 1000 senior chemical
engineering and biochemicals senior and graduate students to conduct intensive search of
global biotech literature, patents(including Chinese herbs)on human cell development,
genetic and molecular biology, immunology, cancer and virus caused major diseases and
aging, developed drugs process design simulation for 30 biotech drug process, including
monoclonal antibodies, interferon's and recombinant DNA applications(6-9)
Human Body Biochemical Plant OSA
Each human body has his unique biochemical plant, hormone productions and decay, and
immune systems (antibodies and interferon's) genetically inherited(design) and responding
differently to the outside environmental impact; pollution's, education's, working and
emotional stress(operations). Even the identical twin, will be different if raised in
different environment, as it is compared to two nearby identical designed chemical plant
reactors catalyst, enzyme activities decay (hormone for human body) behave differently if
it is running under different feed composition, or different climate. .All can be tracked
by real time OSA. Process plant reactors usually replacing catalyst/enzyme as it
activities decay to 60 % level to maintain it's efficiency, as men and women have to
replace hormones as it drop below 60 % to maintain normal body function boost it's immune
system.
Real time simulation of Anti-aging
Hormone therapy:
These group need even more natrual healing, prevention recommended here
Female anti-aging Hormone deficiency estrogen
replacement: Usually found in women after menopause
(after age 40) still with dangers of causing cancer
Male antiaging Hormone (androgen) replacement therapy or testosterone replacement
therapy.
Superhormone therapy: which extend the sterone hormone replacement to other growth
hormone, DHEA, maintaing proper testosterone to estrogen ratio and, malatonin to
revitalize, rejuvenate body function reverse the aging process
Tracking real causes of cancer :Confusing results in linking reproductive systems cancers
(prostate, breast, uterus) to hormones have lead many antiaging patients turned away from
hormone therapy is not justified :
Excellent review of the mechanism of cancer formation by Ames(1) indicated that Gene
mutation, DNA lesion, cell division, ineffective defense systems
Gene Mutation: The real time tracking the real cause of chemicals plant explosion and
runaway polymerization is easily applied to the simulations of cancer etiology (to
identify the target cell and molecule and mutant genes mechanism in malignant cancer cell
formation 30 % caused by tobacco smoking resulted and rodent carcinogens. . Which is well
known now due to the mutation of proto-oncogene (BCR1, BCR2 for breast cancer) runaway
cell growth in the tumor cell, while its regulatory tumor suppressor gene mutation fail to
inhibit the runaway growth ( 50 % of cancer) is similar to the chemical plant free
radicals initiated gas phase explosion or liquid phase polymerization (run away
reactions).
While the anti-oxidants defensive systems is trying to repair the damages caused by gene
mutations caused cancer cell proliferation.
How is DSA/OSA applied to tracking
Aging, Cancer , anti-aging Hormone Therapy chemopreventive programs Development of
antiaging hormone therapy and cancer chemopreventive biochemical plant information
knowledge base
A. Prevent normal cell become tumor or delay on set of cancer cell formation.
B Block tumor or cancer cell formation(antiangiogenesis)
C. Prevent Cancer spreads:
Development of antiaging hormone
therapy and cancer chemopreventive program. real time simulation:
Tracking, simulating each individual diet chemicals
dosage, schedule impact on each antiaging hormone therapy and cancer curing performance,
to setup chemopreventive diet program for each individual antiaging hormone therapy ,
cancer prevention. To reduce or hopefully eventually eliminate animal tests and clinical
trials.
These cocktail program has boosted the immune systems maintain healthy, and confident mood
happier life skipped the mid-age blues and shrinked , eliminated bleeding tumor in 6
months
Understanding Genetic and
environmental impact on aging by Warren Huang paper presented to Keystone, Col.
USA, Feb, 1999