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Home Nobel Idea Causes, Consequences of Aging/Cancer research implementation : This diet, life style help you live up to 140 year healthy, happy
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Molecular, Cellular, Genetic ,
Environmental Impact Approach to
Real Time Operations Simulation Analysis of Human Aging, Hormone Therapy and
Cancer Prevention…
Vera
Huang, Molecular, Cellular Biology
(to who should be addressed to) e-mail
wh3928@yahoo.com
Warren Huang OSA Global Biotech, San
Francisco
This research experience is confirmed
recently by Nobel prize medicine winner
E. Blackburn and C, Greiber work on life style change impact on telemere
length
for aging, disease , cancer prevention
http://nobelprize.org/nobel_prizes/medicine/laureates/2009/press.html
m
and new genes related to human aging,
stress resistance and immune
http://www.reuters.com/article/idUSTRE6304FC20100401?feedType=nl&feedName=ushealth1100
and
http://www.reuters.com/article/idUSTRE6295J820100310?feedType=nl&feedName=ushealth1100
gene map to spot disease
http://www.reuters.com/article/idUSTRE62T0KC20100331?feedType=nl&feedName=ushealth1100
Dr. Warren Huang , pioneer of OSA
Global BioTech, dedicated to the application of APPLO Moonlanding
trackng to model based goal, mission, performance oriented biotech,
biomedical molecualr, cellular, genetic, environmental impact on human aging,
cancer prevention for experiment design, target, gene, target drug search
through directed 300 university senior Chemical Engineering, Biomedical,
Biotech students
review over thousands , molecular biology literature articles and develop, implemented simulation analysis
on disease and aging prevention for over 30 Nobel idea
target molecule, target drugs production
process including antioxidants vitamin E, antibiotics, penicillin, and
recombinant DNA approach to Insulin, Hepatitis, monoclonal antibodies, alpha,
beta interferon, stem cancer cell. The results have been presented to global biotech Conferences
and 1998 Nov. Int'l anti-cancer conference in Greece and Biotech simulation
conference in Lyons, in July.
Colorado, USA, Feb 1999 on Cellular, molecular, genetic approach to
aging and cancer prevention ,,Keystone Molecular Cell Biology ( Dr. Huang
recommended extended C .elegan telemere to molecular, genetic,
cellular environmental impact on human telemere aging ( lab research
has been conducted by Prof. Blackburn, won Nobel Prize 2010 conference, and American Institute of Chemicals Engineers annual meeting, Dallas
, Tx USA, Nov. 1999 Drug, Biotech division on Goal and mission oriented
biotech research, training, This training has been able to complete Ph.D thesis,
Nobel idea research in 3- 6 months
This
report consists of over 25 years research conducted by Dr. Warren Huang,
supervising 300 biochemical engineers in the research of the molecular,
cellular, genetic approach of the causes, cure, prevention of human body
diseases, cancer and aging and the last 5 years extensive review of books,
literatures, and joint research with Vera Huang at Molecular Cell Biology
Department of Univ of California, Berkeley, and attend numerous Nobel prize
winners s on aging Prof. Prusner ( recommended too him to integrating
Molecular, genetic, cellular signal transduction approach to the causes of
biophysics plague formation in brain )on Alzheimer. Prof. Baltimore on Immune, AIDS,
and Prof. Goldstein on Cholesterol control . and Dr. Huang's personal experiences
with his friends associates over 100 years olds
**********************************************************************************************************************************
What is Aging?
The biology of aging start human cell
fail to repair, replicate the damaged cell due to genetic mutation,
environmental oxidative damaging on our DNA, telemere fail to perform necessary signal
transduction to maintain our peak efficiency
Theory of
aging
Why people aging : Our body time clock
start aging, at the age of 25, our growth hormone production ( all cell ,
organ, tissue are mature, stop growing) and most other hormones production start
decay at the rate of 5 % per year.
These hormones are necessary for cell
growth and maintain peak immune defense
At what age people start aging ?
We often heard over the hill at 25. Both
men and women athlets have their peak perfomance before 25, the goldeionn era
for physical performance and beauty, attractiveness. , However the mental
performance can continue to the 70's. as we can we many scientist, literature,
musician still very sharp at 70'- 90s, , the brain weight (neurons) can increase
with ages, as you getting smarter as accumulation of intelligence.
What is the genetic and environmental
impact on aging:
Only 40 % Aging is inherited from parents , while environmental (diet, life
style, and live philiosophy control 60 % it damages the length of
telemere, our longivity molecule
How long can we live and How to delay
aging:
The oldest living person is from Russia
peasant lived 120 years old. (cold country and simple life)
while Japanese has average age of 89,
because have light meal (steamed, boiled) and drink green tea
French lives82also know as light diet,
drink grape wine ( all good cancer, and high blood pressure, heart attack
prevention diet)
aging,
cancer prevention diets: Natural Healing through Food remedy and improved life
style
in stress
resistance
No smoking, no drinking ( only limited
to one glass of wine per day. minimum 6-8 hours sleep
Low fat, low calorie diet have been test
on mouse to extend 40 % of live and observed on human.
Daiy
calorie standard : 1500 , avoid BBQ, charcoal broiled steaks, fired chichen
mill, each mill account for 1000
calorie, and carcinogenic (cancer
causing( must have plenty of vegetables, fruits with such meal or take vitamin C
supplement:
10 vegetables, fruit for cancer and
aging prevention::
Broccoli, Cabbage, Califlower, Tomato,
Corn, Carrots, Soybean/Tofu , Banna, watermelon, grapefruit, grapes
Juices : grape, graefruit, cranberry,
apple, orange, wine and green tea
basic meal, daily rice, bread, egg,
milk, cerel, oatmeal, fish, some lean meat, chicken
drink 4 glases of water:
This diet will kept daily calrie below
1500 and provide necessay vetable, animal protein, vitamins for health
maintanance of in moisture, tender skin, hair, tissue, organ, and immune support
for fight dieseases
This life style and life philosophy help you to live happy long life:
Happiness start from your positive thinking inside you , not the wealth and
friends surround you:
Goal, mission, performances oriented
life, you are always at 18 with full ofd dreams, and passionate of life and
setting goal, mission, performance to achieve your dream of truth, love ,
beauty come true.
Dr. Huang's thesis adviser, Dr. D. F.
Othmer, a world renowned chemical engieeering prof , self made billionaire,
lived very simple fullfilled life, no
entaintaing, (No TV radio in the house, dedicated to his teaching and research
work till he died at 102( reported on NY times We worked till midnight for our
paper for publication and encyclopedia. Last time I met him at his 90 birthday
in Washington DC, We were invited to speak to American Institute of Chemicla
Engineers Diamond Jubilee meeting, he said, he enjoyed lecturing to 600 Beijin
University students
People at 18 have their dreams, as they
getting older, they are frustrated, withdraw, or retired, without any goal,
dreams, they ages, suffered, heart attack, cancer..Anger, depression are the no
1 enemy in cancer and aging(lead to p53 mutation, cell damage (Tumor suppresor )
maintain physical and mentally active,
watch your sitting position,, frequent streching, do not sit and read, watch
TV more than one hour without rest, stretching ( Dr Huang does not wear eye
glass)
You
will be free from cancer, heart failure, Alzheimer , back pain
Aging, diseases,
cancer start with your mind, your emotion and your life style, diet, finally
your environemnt, genetically. This diet and life styles have been used for
most of authors's aged friends living over 100, As most scientist, artists
lived overy 90 on their dreams .
Anti-aging Hormone Therapy without Cancer:
Over 60 % of cancer are caused by
smoking, high fat, high calorie diet and aging. While most of the aging and
cancer problems are caused by sharp hormone decline (woman after menopause, men
after 40 while the body stop producing growth hormone and DHEA, which play
important role in immune defense systems. Hormone replacement therapy to
maintain body normal function of the blood vessel and bones and heart operation
and active happy sex life even at some risk of cancer causes is justified. With
the preventive measure in habit and diets, cancer risks can be minimized (1 to 6
) However, Molecular, Cellular, Genetic Approach to Real Time(DSA/OSA ) Design
and Operations Simulation of Aging, Hormone Therapy, Cancer clinical test in
animal and human body is vital for fighting Against aging and cancer.
save 60 % of our cancer patients life
with more than 60 % survival rate!
DSA/OSA applied to Real time Simulation
and control , preventive maintenance of refinery, petrochemicals, and biotech
process performances
Dr. Warren Huang pioneered OSA (Design
and Operations Simulations Analysis) by extended the problem solving decision
analysis of Operations Research used by US Aerospace Automatic Guidance.
Tracking, Simulation, applying artificial intelligence pattern recognition,
adaptive filtering and control to challenge the unknown and impossible task for
the Apollo moon landing to Chemical and biotech systems simulation.
As he implemented goal, mission,
performance oriented multidisciplinary OSA planning, execution teams to develop,
implement decision support to Bethel and Mobil New York office's and Stauffer
Chemicals (subsidiary of Rhone Poulenc) process computer and simulation methods
section developed, implemented refinery, petrochemicals, pharmaceuticals process
design and operations simulation and control systems by integrating the
chemical, biochemical reactions engineering principle into senior process
engineers 20 years plant design, operating, equipment preventive maintenan ce's
pattern recognition, human mind reasoning knowledge and full range plant reactor
catalyst, enzyme loading, startup , daily reactor catalyst activity decay,
operating, maintenance history data, experiences as the information knowledge
base. These knowledge based process simulation systems were used directly for
supporting senior engineers daily global refinery, petrochemicals plant design,
real time online tracking, simulation of reactors and equipment design and
operating environment and maintenance impact on the reaction yields, performance
improvement and on the job training, without going through laboratory and pilot
plant tests().( a well maintained and regular catalyst, enzyme replacement plant
can run 50 years life with minimum accidents compare to average 10
Real time Tracking of causes
of Aging, human cancer and hormone therapy, drug productions
Warren extended OSA to molecular,
genetic, level human biochemical plant design and operations simulation(7-9) for
causes of aging, cancer and hormone therapy, drugs production process
simulations 14 years ago. He directed over 1000 senior chemical engineering and
biochemicals senior and graduate students to conduct intensive search of global
biotech literature, patents(including Chinese herbs)on human cell development,
genetic and molecular biology, immunology, cancer and virus caused major
diseases and aging, developed drugs process design simulation for 30 biotech
drug process, including monoclonal antibodies, interferon's and recombinant DNA
applications(6-9)
Human Body Biochemical Plant OSA
Each human body has his unique
biochemical plant, hormone productions and decay, and immune systems (antibodies
and interferon's) genetically inherited(design) and responding differently to
the outside environmental impact; pollution's, education's, working and
emotional stress(operations). Even the identical twin, will be different if
raised in different environment, as it is compared to two nearby identical
designed chemical plant reactors catalyst, enzyme activities decay (hormone for
human body) behave differently if it is running under different feed
composition, or different climate. .All can be tracked by real time OSA. Process
plant reactors usually replacing catalyst/enzyme as it activities decay to 60 %
level to maintain it's efficiency, as men and women have to replace hormones as
it drop below 60 % to maintain normal body function boost it's immune system.
Real time simulation of
Anti-aging Hormone therapy:
These group need even more natrual
healing, prevention recommended here
Female anti-aging Hormone
deficiency estrogen replacement: Usually found in women after menopause (after
age 40) still with dangers of causing cancer
Male antiaging Hormone (androgen)
replacement therapy or testosterone replacement therapy.
Superhormone therapy: which extend the
sterone hormone replacement to other growth hormone, DHEA, maintaing proper
testosterone to estrogen ratio and, malatonin to revitalize, rejuvenate body
function reverse the aging process
Tracking real causes of cancer
:Confusing results in linking reproductive systems cancers (prostate, breast,
uterus) to hormones have lead many antiaging patients turned away from hormone
therapy is not justified :
Excellent review of the mechanism of
cancer formation by Ames(1) indicated that Gene mutation, DNA lesion, cell
division, ineffective defense systems
Gene Mutation: The real time tracking
the real cause of chemicals plant explosion and runaway polymerization is easily
applied to the simulations of cancer etiology (to identify the target cell and
molecule and mutant genes mechanism in malignant cancer cell formation 30 %
caused by tobacco smoking resulted and rodent carcinogens. . Which is well known
now due to the mutation of proto-oncogene (BCR1, BCR2 for breast cancer) runaway
cell growth in the tumor cell, while its regulatory tumor suppressor gene
mutation fail to inhibit the runaway growth ( 50 % of cancer) is similar to the
chemical plant free radicals initiated gas phase explosion or liquid phase
polymerization (run away reactions).
While the anti-oxidants defensive
systems is trying to repair the damages caused by gene mutations caused cancer
cell proliferation.
How is DSA/OSA applied to
tracking Aging, Cancer , anti-aging Hormone Therapy chemopreventive programs
Development of antiaging hormone therapy and cancer chemopreventive biochemical
plant information knowledge base
A. Prevent normal cell become tumor or
delay on set of cancer cell formation.
B Block tumor or cancer cell
formation(antiangiogenesis)
C. Prevent Cancer spreads:
Development of antiaging
hormone therapy and cancer chemopreventive program. real time simulation:
Tracking, simulating each
individual diet chemicals dosage, schedule impact on each antiaging hormone
therapy and cancer curing performance, to setup chemopreventive diet program for
each individual antiaging hormone therapy , cancer prevention. To reduce or
hopefully eventually eliminate animal tests and clinical trials.
These cocktail program has boosted the
immune systems maintain healthy, and confident mood happier life skipped the
mid-age blues and shrinked , eliminated bleeding tumor in 6 months
Understanding Genetic and environmental impact on aging ( Blackburn
2010 Nobel experiment on aging research) by Warren Huang
paper presented to Keystone, Col. USA, Feb, 1999
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