'" Human Disease, Aging, Therapy Operations Simulation"

The achievement of genetic and molecular biology in modern biotech has brought human body biochemical plant even closer to refinery, petrochemicals process plant design and operations .Warren's successful direct application of knowledge based online refinery, petrochemicals process plant OSA (Operations Simulation Analysis) and computer control to improve plant operating efficiency and plant life at reduced accident, interruptions without any laboratory or pilot plant tests, or equipment retrofit through OSA guided improved operating guideline and preventive maintenance.

With the help from our genetic and molecular level simulation of CNS, PNS and Hormones integrated control of organs and tissues functions , which dominate our health, longevity, and disease.

Diseases and Aging can easily be identified through the malfunction of the systems by real time tracking and simulation of these central and regulatory control systems Which can be caused by inherited genetic defect ,or damaged by environmental polluted chemicals free readical attack resulted uncogene trickled cancer or virus infection, damaged immune systems, or is caused by scrapie prion turn on to destroy the neurons resulted spongy form. Knowledge based Operations Simulation Analysis of Disease, aging and therapy again save time wasted in clinical trials, animal test. The recent breakthrough in gene therapy by direct injection of tumor suppresor genes and antigens,bombard it with activated Iodine on monoclonal antibody to destroy the cancer cells in 24 hours.,without any clinical trial or animal tests,. which already copy the OSA online process plant troubleshooting; solve the plant operating problem instantly without interruption

With the help from human genome projects, which identify DNA sequences of the known disease provide OSA tracking and simulation of the genetic and molecular level enzyme catalyzed organic synthesis reactions surrounding the real cause of human Diseases and Aging, and the therapeutic mechanism very valuable information resources for the effective cure, therapy of aging and major disease

The first step in building knowledge based human disease, aging, therapy OSA systems is to form goal, mission, performance oriented cross-functional OSA teams, then start the collection of entire medical history, pathology, pathogenic data, therapeutic and clinical trials history and the specialists experiences from various cell development,genetics, immunology, pathologist, and MD's and build up the knowledge based human disease, aging, therapy information systems, knowledge based OSA decisions simulators can then be developed to identify the real cause and curing therapy approach for the disease and aging and prevention directly, hopefully without going through animal tests and or clinical trials

This approach can easily applied to the simulation of animal tests or clinical trial, like the prion related diseasesimulation in mouse and human brain simultaneously to identify the real cause and way to cure it.

References:
Huang,W." Improve Process by OSA",-May 1980, Hydrocarbon Processing
Huang,W." OSA/DSA Approach to Biotech and Recombinant DNA",- int'l Biotech Conference, Sept. 1985, Singapore
Huang,W" OSA/DSA Approach to Chemicals and Biotech Reactors", to ACHEMA, Sept. 1991, Frankfurt, Germany.
Huang,W, Huang, V." Human Body Biochemical Plant Design, Operations Simulation"- Biotech Simulation Conf, July, 1998, Lyon,France
Huang,W, Huang, V"Aging, Disease, Therapy Operations Simulation",- Biotech Simulation Conf, July, 1998, Lyon,France

To be presented to Int'l  Biotech Simulation conference  July  21-25, Lyon, France

Contact Information E-mail :  whuang@osawh.com  Fax : 1-510-524-4484(  San Francisco, USA)