Optimizing Death and Growth Receptor-Mediated Processes in causes and cures of Cancer and
Aging
Vera Huang, Dept. of Molecular and Cell Biology, University of California ,
Berkeley, Ca. USA Email
vera324@yahoo.com
Warren Huang OSA Global Biotech, San Francisco ,Ca Fax: 1-510-524-4484
(Corresponding author) e-mail
wh3928@yahoo.com ,
osawhh@citiz.net
Recent progress in growth and death signal transduction path ways has
made giant step toward the understanding of causes, cures of human cancers and aging.
Genetics accounts only for 40 % of the causes of aging and cancer while 60 % comes from
life style, environment resulted in cell damage, gene mutation in signal transduction
pathway systems, which in turn lead to abnormal cell growth (cancer) and death (aging).
Steroid and growth hormones peaking out around the age of 25, which play key role in gene
regulation, expression, cell cycle control and maintaining vitality in fighting cell
damage and mutation in human immune system, organ, tissue, brain and mood at its peak
performance through receptors.
Goal, mission, performance oriented joint MCB-Medical research in the simulation of the
optimal control of growth factors and caspase signal transduction pathways, lead to
identify the target molecules and genes and understanding of etiology and target drugs of
numerous cancer (selectively activated cell death) and aging ( premature neuron death
caused Alzheimer can be prevented by caspase inhibitors). Complete knowledge in the
functions of tumor suppressors, caspases, decoy receptors already lead to most powerful,
effective gene delivery drugs for human cancer, aging prevention, cures which helps
hormone replacement in anti-aging while minimize cancer risks
To be presented to American Institute of Chemical Engineers annual conference on
Biotech, Pharmaceutical education, Dallas, Texas, Nov, 8, 1999 and submitted to American
Society of Cell Biology, Washington DC, Dec. 15, 1999